NanoMixer

FAQs and Tips

Troubleshooting:

Mechanical Faults

1.Backflow at Inlet
Symptom: Liquid flows back at the inlet while the syringe is in the extrusion stroke.
Cause: The inlet check valve has failed.
Solution: Replace the check valve.

2. Backflow at Outlet
Symptom: Liquid flows back at the outlet while the syringe is in the suction stroke.
Cause: The outlet check valve has failed.
Solution: Replace the check valve.

3. Microfluidic Chip Microchannel Blockage
Symptom: Sudden rise in internal system pressure causes connected capillaries to detach due to high pressure.
Cause: The microchannels on the chip surface are blocked.
Solution: Clean the chip microchannels.

4. Insufficient Suction Due to Air in Tubing
Symptom: The syringe does not fully fill, and air is present in the liquid.
Cause: Air is trapped inside the tubing system.
Solution: To degas the system, push the liquid upward in the syringe while loosening the outlet check valve to release trapped air.
Once the liquid flows steadily, tighten the valve, and repeat this process two to three times until all air is expelled.

Electrical Faults

1.Red Power Switch (PWR) Not Lit
1) Check if the fuse is blown; replace if necessary.
2) Check the device power connection; reconnect if faulty.
3) Check the wall socket; ensure the plug is fully inserted.

2. Clicking “Start” on the Main Interface Has No Response
1) Turn off the power and wait 30 seconds before restarting.
2) The system will rebuild, which takes a few seconds.
If the problem persists after restarting, contact after-sales service for assistance.

Equipment Maintenance

1. Repair and Preventive Maintenance
The required frequency of repair and preventive maintenance depends
on usage and the specific applications performed.
It is generally recommended to schedule maintenance and preventive
servicing at least once per year. Adhere to the recommended maintenance intervals.
If any component fails, it is recommended to replace it immediately to
prevent further damage to the system. Following these guidelines will help maximize the system’s service life.

2 Daily Cleaning
The syringe holder and chip bracket are the most common areas for spills, droplets, and material buildup. Surfaces can be wiped with ethanol or isopropanol. If fluid flows along the syringe holder into the interior of the instrument, there is no need to stop the machine during operation because the system is designed with a dry-wet separation; small amounts of liquid will not affect safety. After stopping the instrument, wipe the area with a clean, lint-free cloth. If fluid splashes onto the plastic housing, wipe it promptly to keep the exterior dry and avoid damage to the paint.

To clean the instrument body, cover, and all internal components, wipe surfaces with any of the following:
a. Warm water with a mild, non-abrasive detergent
b. Ethanol
c. Isopropanol

Use a soft cloth to wipe the surfaces, avoiding scratches that could affect the appearance of the instrument.