High Pressure Micromix Homogenizer MixGenizer
Description: A homogenizer designed especially for mixing and homogenizing the sample fluids from two or more inlet ports.
Cell disruption
Micro/nanoencapsulation in polymers, liposomes and oils
Solid dispersion and suspension, deagglomeration
Small (integrated design delivers the light weight and small dimensions)
Smart (programming control systems confer diligent functions: controlled inlet volume ± 0.1mL; auto stop with time/volume)
Silent (noiseless performance)
Strong (more than 100 mL/min at 30,000 psi)
CE compliant and RoHS compliant
Specification
| Catalog No. | MixGenizer-30k | ||||
| Max. Flow Rate | 100mL/min | ||||
| Min. Sample | 1mL | ||||
| Max. Pressure | 30,000psi | ||||
| Dimensions(cm) | 85×50×35 | ||||
| Weight | 58kg (128lbs) | ||||
| Max. Temp. | 80ºC (176ºF) | ||||
| Power | 220V/110V | ||||
| Cleaning | Flush to clean | ||||
| Application | Nano emulsion, fat emulsion, liposome, cell disruption, nano dispersion, deagglomeration, nano precipitations | ||||
| Features | Notable shear rate; powerful micromix; greater repeatability; guaranteed scalability | ||||
Features
| Parts | Y-type diamond mixing chamber | ||||
| Control System | High pressure programming control systems: touch screen, speed control, auto stop control by volume, time, pressure or temperature, settable volume control as small as 1mL, display of flow rate and time, overload protection | ||||
| Pressure Gauge | Digital display on the touch screen | ||||
| Inlet Type | 1/4″ HP coupling | ||||
| Outlet Type | 1/4″ HP coupling | ||||
| Inlet Speed | 0-100mL/min ± 0.1mL/min | ||||
| Mixing Accuracy | 1% | ||||
| Mixing Arrange | 25%-100% | ||||
| Inlet Reservoir | 20mL syringe or S/S cylinder | ||||
| Outlet Reservoir | 20mL syringe or S/S cylinder | ||||
| Product Material | 316L stainless steel, tungsten carbide, viton, teflon | ||||
| Material Standard | Sanitary grade, FDA, GMP | ||||
| Warranty | 1 year against any manufacturing defects | ||||
| Option Features | |||||
| Parts | High pressure extruders, Y-type diamond mixing chamber with cooling, heat exchanger | ||||
| Control System | Gradient mixing, three or four components | ||||
| Detector | Pressure gauge, pressure transducer up to 8 options, temperature transducer up to 8 options | ||||
| Outlet Type | Tri-clamp, luer or flow sorter | ||||
| Heat Exchanger | HPE-100-3D; HPE-150-3D; HPE-200-3D | ||||
| Inlet Reservoir | 20mL, 50mL, 100mL, 200mL syringe, 300mL, 500mL S/S cylinder, jacketed glass cylinder or online | ||||
| Outlet Reservoir | 20mL, 50mL, 100mL, 200mL syringe, 300mL, 500mL S/S cylinder, jacketed glass cylinder or online | ||||
| Cylinder | Titanium high pressure cylinder (resistant to strong acid and base) | ||||
How to Use
Genizer’s flow Sorter for MixGenizer can collect samples with designed pressure or volume.

A flow sorter allows the user to select (gate) a flow based on pressure or volume.
The user can set the pressure, so the mixed sample above the pressure and mixed sample below the pressure can be separated.
The user can also set the percentage of volume, so the mixed sample within the percentage of volume and mixed sample outside
the percentage of volume can be separated.
FAQs and Tips
Our design has minimized the occurrence of air-blocking, chamber-blocking and overload.
However, the improper operation of the homogenizer can still induce the errors and cause damage to the homogenizer.
Air Blocking
Symptom: there is no pressure and no sucking from inlet
Prevention: do not run with empty inlet
Reason: there is air inside the pump
Solutions:
1) In the customer setup, push the “Degas” button
2) Running 50mL water with 50% speed
3) Push the ball into the inlet valve with a pin

Chamber Blocking
Symptom: overload of the pressure
Prevention: pre-treat the sample carefully; reduce the speed
Reason: there are aggregates or particles in the sample; too high a speed
Solutions:
1) Reverse flow the outlet valve with 100mL water with low speed
2) Reverse flow the chamber with water from low to high speed
Overload
Solutions:
1) Reduce the speed and close the power, wait 30 sec and restart
2) Wash with water or solvent
3) Run with clean and homo-disperse sample
No Response
Symptom: the equipment does not respond when click the “Start” button on the touch screen
Solutions:
1) Turn off the power supply and wait for 30 seconds to restart
2) If there is still no response, please check the power input. The power supply of the equipment is 220V. When the external power supply is 110V, a power converter shall be used. And its INPUT port should connect to 110V while the OUTPUT port connect to 220V
Air blocking rarely causes damage to the NanoGenizer; however, the chamber blocking is harmful to the pump because of overloaded pressure in an instant.
1) Pretreat the sample carefully, and always use a clean and homo-disperse sample
2) Adjust the pressure from low to high
3) For safety, do not point the inlet or outlet of high pressure devices and equipment supplied by Genizer, including high pressure homogenizer, extruder, interaction chamber and valve, to any personnel or object that may affect safety or induce property loss.
Tips:
For facilitating the user applications, the two ports in the high pressure cylinder of the NanoGenizer are exchangeable for inlet and outlet.
| Cells | Mammalian cell![]() |
Insect cell![]() |
Bacteria cell![]() |
Yeast cell![]() |
Algae cell![]() |
Spore![]() |
| Sample | CHO|Hela | Sf9|Sf21|H5 | E. Coli | Yeast | Green algae | Ganoderma |
| Pressure | 600-800bar 8500-11500psi | 600-1000bar 8500-14500psi | 800-1000bar 11500-14500psi | 1200-1400bar 17500-20000psi | 1200-1500bar 7500-21500psi | 1300-1600bar 18500-23000psi |
| Chamber | F20Y, F20Y-RT | F20Y, F20Y-RT | F20Y, F20Y-RT | F20Y, F12Y | F20Y, F12Y | F20Y, F12Y |
| Emulsions | Oil in water emulsions![]() |
Water in oil emulsions![]() |
Oil emulsion![]() |
Food![]() |
Liposome (o/w)![]() |
Liposome (w/o)![]() |
| Sample | Fat emulsion | Cosmetics | Fuel | Milk | DOX | DNA|lipopolyplex |
| Pressure | ~20,000psi | ~10,000psi | ~20,000psi | ~10,000psi | ~20,000psi | ~8,000psi |
| Chamber | F20Y, F12Y | F20Y | F20Y, F12Y | F20Y | F20Y, F12Y | F20Y |
| Dispersions | Pigments![]() |
Creams![]() |
Battery![]() |
Particle aggregation![]() |
Graphene![]() |
Nanotubes![]() |
| Sample | Inks, Coatings | Creams | Lithium/Solar cell | Nano fibril | Graphene | Carbon Nanotubes |
| Pressure | ~25,000psi | ~20,000psi | ~20,000psi | ~25,000psi | ~20,000psi | ~20,000psi |
| Chamber | F20Y, F12Y | F20Y, F12Y | F20Y, F12Y | F20Y, F12Y | F20Y, F12Y | F20Y, F12Y |



























