NanoGenizer-Quad (Quad Pump)
Description: Laboratory Quad-Pump testing up to 30,000 psi with electric power.
Cell disruption
Micro/nanoencapsulation in polymers, liposomes and oils
Solid dispersion and suspension, deagglomeration
Small (integrated design delivers the light weight and small dimensions)
Smart (programming control systems confer diligent functions: auto stop with time/volume)
Silent (noiseless performance)
Strong (6-27L/hr)
CE compliant and RoHs compliant
Specification
| atalog No. | NanoGenizer-Quad |
| Flow Rate | 6-27L/hr |
| Min. Sample | 5mL |
| Max. Pressure | 30,000psi |
| Dimensions(cm) | 92 × 69 × 40 |
| Weight | 117 kg (258 lbs) |
| Max. Temp. | 80ºC (176ºF) |
| Power | 220V |
| Cleaning | Flush to clean |
| Application | Nano emulsion, fat emulsion, liposome, cell disruption, nano dispersion, deagglomeration |
| Features | Digital display of pressure or pressure gauge |
Features
| Parts | Y-type diamond interaction chamber with cooling option |
| Control System | High pressure programming control systems: touch screen, speed control, auto stop control by volume, time, pressure or temperature, display of flow rate and time, overload protection |
| Pressure Gauge | Digital display on the touch screen |
| Inlet Type | Tri-clamp |
| Outlet Type | Tri-clamp |
| Inlet Reservoir | 500mL S/S cylinder |
| Outlet Reservoir | Plastic hose |
| Product Material | 316L stainless steel, tungsten carbide, viton, teflon |
| Material Standard | Sanitary grade, FDA, GMP |
| Warranty | 1 year against any manufacturing defects |
| Option Features | |
| Parts | High pressure extruders, homogenizing valves, heat exchanger |
| Control System | Mechanical control: speed, start, stop controls |
| Detector | Pressure gauge, pressure transducer up to 8 optional, temperature transducer up to 8 optional |
| Outlet Type | Tri-clamp or luer |
| Inlet Reservoir | 10mL, 20mL, 50mL, 100mL, 200mL syringe, S/S cylinder, jacketed glass cylinder or online |
| Outlet Reservoir | 10mL, 20mL, 50mL, 100mL, 200mL, syringe, S/S cylinder, jacketed glass cylinder or online |
| Cylinder | Titanium high pressure cylinder (resistant to strong acid and base) |
How to Use
Disassemble the seal

Assemble the seal

FAQs and Tips
Our design has minimized the occurrence of air-blocking, chamber-blocking and overload.
However, the improper operation of the homogenizer can still induce errors and cause damage to the homogenizer.
Air Blocking
Symptom: there is no pressure and no sucking from inlet
Prevention: do not run with empty inlet
Reason: there is air inside the pump
Solutions:
1) In the customer setup, press the “Degas” button.
2) Running 50mL water with 50% speed
3) Push the ball into the inlet valve with a pin

Chamber Blocking
Symptom: overload of the pressure
Prevention: pre-treat the sample carefully; reduce the speed
Reason: there are aggregates or particles in the sample; too high a speed
Solutions:
1) Reverse flow the outlet valve with 100mL water with low speed
2) Reverse flow the chamber with water from low to high speed
Overload
Solutions:
1) Reduce the speed and close the power, wait 30 sec and restart
2) Wash with water or solvent
3) Run with clean and homo-disperse sample
No Response
Symptom: the equipment does not respond when click the “Start” button on the touch screen
Solutions:
1)Turn off the power supply and wait for 30 sec to restart
2) If there is still no response, please check the power input. The power supply of the equipment is 220V. When the external power supply is 110V, a power converter shall be used. And its INPUT port should connect to 110V while the OUTPUT port connect to 220V
Air blocking rarely causes damage to the NanoGenizer; however, the chamber blocking is harmful to the pump because of overloaded pressure in an instant.
1) Pretreat the sample carefully, and always use a clean and homo-disperse sample
2) Adjust the pressure from low to high
3) For safety, do not point the inlet or outlet of high pressure devices and equipment supplied by Genizer, including high pressure homogenizer, extruder, interaction chamber and valve, to any personnel or object that may affect safety or induce property loss.
Tips:
For facilitating the user applications, the two ports in the high pressure cylinder of the NanoGenizer are exchangeable for inlet and outlet.
| Cells | Mammalian cell![]() |
Insect cell![]() |
Bacteria cell![]() |
Yeast cell![]() |
Algae cell![]() |
Spore![]() |
| Sample | CHO|Hela | Sf9|Sf21|H5 | E. Coli | Yeast | Green algae | Ganoderma |
| Pressure | 600-800bar 8500-11500psi | 600-1000bar 8500-14500psi | 800-1000bar 11500-14500psi | 1200-1400bar 17500-20000psi | 1200-1500bar 7500-21500psi | 1300-1600bar 18500-23000psi |
| Chamber | F20Y, F20Y-RT | F20Y, F20Y-RT | F20Y, F20Y-RT | F20Y, F12Y | F20Y, F12Y | F20Y, F12Y |
| Emulsions | Oil in water emulsions![]() |
Water in oil emulsions![]() |
Oil emulsion![]() |
Food![]() |
Liposome (o/w)![]() |
Liposome (w/o)![]() |
| Sample | Fat emulsion | Cosmetics | Fuel | Milk | DOX | DNA|lipopolyplex |
| Pressure | ~20,000psi | ~10,000psi | ~20,000psi | ~10,000psi | ~20,000psi | ~8,000psi |
| Chamber | F20Y, F12Y | F20Y | F20Y, F12Y | F20Y | F20Y, F12Y | F20Y |
| Dispersions | Pigments![]() |
Creams![]() |
Battery![]() |
Particle aggregation![]() |
Graphene![]() |
Nanotubes![]() |
| Sample | Inks, Coatings | Creams | Lithium/Solar cell | Nano fibril | Graphene | Carbon Nanotubes |
| Pressure | ~25,000psi | ~20,000psi | ~20,000psi | ~25,000psi | ~20,000psi | ~20,000psi |
| Chamber | F20Y, F12Y | F20Y, F12Y | F20Y, F12Y | F20Y, F12Y | F20Y, F12Y | F20Y, F12Y |























